I have to think it would have a lasting effect. I would have been interested to see what happened to Barty Crouch Jr. after he went off Polyjuice in GoF.
Crouch obviously gained the ability to use Moody's magical eye when he used Polyjuice. How much of that involved altering his brain in order to replace his normal eye with a magical one?
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Crouch obviously gained the ability to use Moody's magical eye when he used Polyjuice. How much of that involved altering his brain in order to replace his normal eye with a magical one?
Also, is Polyjuice addictive?